| Date | Home | Score | Away | Venue |
| November 2011 | ||||
| 11.11.11 | Racing Metro | Blues | ||
| 12.11.11 | Scarlets | Castres | Parc y Scarlets | |
| Ospreys | Biarritz | Liberty Stadium | ||
| 18.11.12 | N. Saints | Scarlets | ||
| Blues | L. Irish | Cardiff City Stadium | ||
| 19.11.12 | Treviso | Ospreys | ||
| December 2011 | ||||
| 09.12.11 | Blues | Edinburgh | Cardiff City Stadium | |
| 10.12.11 | Scarlets | Munster | Parc y Scarlets | |
| Saracens | Ospreys | Wembley Stadium | ||
| 16.12.11 | Edinburgh | Blues | Murrayfield | |
| Ospreys | Saracens | Liberty stadium | ||
| 18.12.11 | Munster | Scarlets | Thomond Park | |
| January 2012 | ||||
| 13/14/15 | Scarlets | N. Saints | Parc y Scarlets | |
| L. Irish | Blues | |||
| Ospreys | Treviso | Liberty Stadium | ||
| 20/21/22 | Castres | Scarlers | ||
| Blues | Racing Metro | Cardiff City Stadium | ||
| Biarritz | Ospreys | |||
| April 2012 | ||||
| 6/7/8 | Quarter Finals | |||
| 27/28/29 | Semi Finals | |||
| May 2012 | ||||
| 19/20 | Final (Twickenham Stadium, London) | |||